Job Description

JOB DESCRIPTION

Job Role: Upstream/Protein Expression

Department: SARC - CEPA

Job Location: Bangalore

About Syngene:

Syngene ( ) is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply.

At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures, and SOPs, in letter and spirit.

Mandatory expectation for all roles as per Syngene safety guidelines

• Overall adherence to safe practices and procedures of oneself and the teams aligned.
• Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company\'s integrity & quality standards.
• Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
• Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
• Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self.
• Compliance to Syngene\' s quality standards at all times.

Core Purpose of the Role: We are seeking a skilled and enthusiastic mammalian cell culture scientist to join the mammalian cell culture group in the Protein tech - SARC Biology, a multidisciplinary team with capabilities in molecular cloning, expression, and purification of proteins, including antibodies, bispecific and microbially expressed proteins. The ideal candidate will have broad laboratory training, deep scientific curiosity and a positive approach to working in a team-based research environment along with a track record of creative problem-solving and enthusiasm for taking on difficult research challenges.

Role Accountabilities:

• Strong knowledge and experience with mammalian cell culture technologies and theory.
• Experience in stable and transient transfection for recombinant protein/antibody expression is a must. Should have worked with and maintained variety of mammalian cell lines, such as CHO, HEK etc. Well versed with aseptic techniques required to work in a cell culture laboratory.
• Perform adherent and suspension cell culture, support upstream process development and process characterization activities.
• Should have experience working with Wave bioreactors and good knowledge of feed optimization.
• Experience in cell culture media and feed development and running pilot scale bioreactor is a plus. Also desirable is knowledge and experience in baculovirus based insect cell expression.
• Familiarity with flow cytometry (FACS), western blot, automated - cell imaging system, basic antibody characterization assays and high throughput screening.
• Should be able to design, execute and troubleshoot on cell culture, transfection related and cell line generation projects.
• Ability to learn new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies.
• Work according to established Standard Operating Procedure (SOP) and regulatory guidance.

Syngene Values: All employees will consistently demonstrate alignment with our core values

• Excellence
• Integrity
• Professionalism

Experience:

• 3-6 years

Educational Qualification:

• MSc./M.Tech in biotechnology, cell biology, biochemistry or similar scientific fields.

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.

Syngene International