Job Description

Designation: Senior Research AssociateJob Location: BengaluruDepartment: Discovery BiologyAbout SyngeneIncorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene\' s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.Job Purpose:The incumbent will perform protein expression and purification from various expression systems, following ALCOA+ principles and Data integrity policy.Key Responsibilities:

• Protein expression involving E. coli & Mammalian cell lines (Insect cell work is highly appreciated) and purification involving small & large scales of batch sizes (2L-20L).
• Experience with tagged and non-tagged genes for expression and purification, involving expertise in hands-on ion-exchange chromatography, hydrophobic ion chromatography, size-exclusion chromatography, analysis by SDS-PAGE & Western blots, ELISA assays.
• The candidate should be independently able to purify a protein in a multi-step purification (~2-5 steps) and have negligible endotoxin amounts.
• The candidate should maintain up-to date lab note books/eLNs at the time of completing the experiment.
• Ability to work in a team is important and the candidate should demonstrate this objective.
• Sound knowledge of protein expression.
• Any experience with techniques like Western blotting, ELISA.
• Basic working experience in protein characterization, various HPLC techniques and experience in upstream process.

Educational Qualification: M.Sc/M.Tech in Biotechnology or related disciplines.

• Protein purification using AKTA Pure & AKTA Avant systems, process development, experience in Affinity, Ion-exchange, HIC chromatography, Column packing and tangential flow filtration.
• Excellent communication with upstream and analytical team.
• Diligent documentation skills and experience writing detailed Lab Notebooks.
• Expert in analytical techniques and handling of the relevant instruments.

Experience: 3-6 years post qualificationBehavioral Skills:

• Should be well versed in verbal and written communication, should be a team player.
• Should be focused towards results and deliverables.
• Should have a high moral framework (ethics code) and high data integrity sense.

Equal Opportunity Employer:It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.

Syngene International