Job Description

About the jobJubilant Bhartia GroupJubilant Bhartia Group is a global conglomerate founded by Mr. Shyam S Bhartia and Mr. Hari S Bhartia with strong presence in diverse sectors like Pharmaceuticals, Contract Research and Development Services, Proprietary Novel Drugs, Life Science Ingredients, Agri Products, Performance Polymers, Food Service (QSR), Food, Auto, Consulting in Aerospace and Oilfield Services. Jubilant Bhartia Group has four flagships Companies- Jubilant Pharmova Limited, Jubilant Ingrevia Limited, Jubilant FoodWorks Limited and Jubilant Industries Limited. Currently the group has a global workforce of around 43,000 employees.About Jubilant BiosysJubilant Biosys Ltd is a part of the Jubilant Pharmova family of companies with RD centres in India and business offices in Asia and North America. With our global reach, Jubilant Biosys provides comprehensive drug discovery services and contract research servicesfrom target discovery to candidate selection and with flexible business models (FFS, FTE and risk shared)in partnership with leading worldwide healthcare companies.With a clear scientific focus in oncology, metabolic disorders, central nervous system (CNS) diseases, pain and inflammation, Jubilant Biosys has rapidly emerged as a leading collaborator for pharmaceutical and biotechnology companies worldwide. In each of these therapeutic areas, Jubilant Biosys has developed a deep level of expertise in discovery informatics, computational chemistry , medicinal chemistry, structural biology , biology,in-vivo,in-vitromodels and translational sciences. Combined with strong clinical development and manufacturing capabilities from other Jubilant subsidiaries, Jubilant Biosys has risen as a fully integrated contract research organization in India and headquartered at Bengaluru with end-to-end solutions.Our ability to be the preferred collaborator in the drug discovery domain is sustained by our commitment to comply with and continually improve our quality systems and to provide the following services:Contract ResearchPreclinical CRODrug DiscoveryVirtual ScreeningProtein CrystallizationToxicology In-vitroADMEMedicinal ChemistrySynthetic Developmental ChemistryPharmacologyJubilant Biosys collaborates with the worlds leading pharmaceutical, biotech companies, academic institutions and research foundations.Find out more about us at www.jubilantbiosys.comThe PositionOrganization : - Jubilant BiosysDesignation Level: - Research Associate/ Sr. Research Associate (A3/A4)Location: - Greater NoidaDepartment: - DMPKKey ResponsibilitiesIn Vitro ADME studiesRead and understand various in vitro ADME protocolsConduct in vitro stability (liver microsomes, plasma and in any other relevant matrix, chemical stability) experiments for new chemical entitiesConduct the following in vitro ADME experimentslogP, logD, pKa measurementsCYP induction and inhibition assaysPermeability determinations (Caco-2, MDCK etc) in relevant cell linesCYP phenotyping in purified enzyme systemsSolubility determinations (kinetic, thermodynamic, simulated fluids)Bioanalysis :Read and understand the bioanalysis sections in the study protocolsLC-MS/MS and HPLC-UV/PDA method development and validation (partial and complete)Developing fit-for-purpose LC-MS/MS methods for routine in vitro sample analysisExtracting data from the instrument, conducting bioanalytical QC and sharing of report with the stakeholders within the DMPK departmentExperience in handling bioanalytical method development for various matrices with focus on in vitro samples; understanding to handle plasma, blood, various tissues, urine, faeces etc. is a plus but not mandatory.Development LC-MS/MS methods for biochemical and cell based screening of NCEs is a plus but not mandatoryGeneral LC-MS/MS and HPLC maintenance and troubleshootingData analysis and report generation:Understand the quality of bioanalytical dataConduct data analysis employing Phoenix WinNonLin software is a plus but not mandatoryAbility to calculate in vitro results/ parameters on excel spreadsheetsReport generation (excel format, word format and PowerPoint presentation) and sharing with the line managerGenerate reports in both GLP and non-GLP formats (based on the requirement)Person ProfileQualification: -M.Sc /M.Tech (Biochemistry, Pharmaceutical Chemistry, Biotech background)Master in Pharmacy (M.Pharm)Experience: -2- 6 years of relevant experience.Experience in a drug discovery industry/ CRO in DMPK department.Jubilant is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to age, ancestry, citizenship, colour, gender identity or expression, genetic information, marital status, medical condition, national origin, political affiliation, race, ethnicity, religion or any other characteristic protected by applicable local laws, regulations and ordinances.Lifelancer ( ) is a talent-hiring platform in Life Sciences, Pharma and IT. The platform connects talent with opportunities in pharma, biotech, health sciences, healthtech, data science and IT domains.Please use the below Lifelancer link for job application and quicker response.

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