Key role: Development of multiplex based cytokine release assay and Elispot/ flow cytometry based T cell assays to measure the innate and adaptive Immunogenicity of synthetic peptide products.
Job Responsibilities:
Responsible for study sample analysis for all pipeline products.
Isolation of PBMC from whole blood and maintenance of commercial cell lines.
Data compilation, QC & Statistical analysis of data.
Preparation of standard operating procedures (SOP), method development reports (MDR) and analytical test procedures (ATP).
Responsible for operating and maintaining analytical laboratory in compliance with GLP regulations.
Responsible for the operation and maintenance of the Flow Cytometry, Multiplex, ELISPOT and other instruments.
Management of chemicals, consumables & critical reagents inventory. Performing calibration of instruments and equipment. Troubleshooting instrument performance and equipment issues.
Technical Skills (Required):
Sound knowledge of Immunology, Cell biology and Animal cell culture is mandatory.
Experience on cell based assays is mandatory.
Desirable Skills (Optional):
Experience of handling flow cytometry is highly desirable.
Experience of handling luminex/ ELISA/ Elispot/ statistical software is a value addition.
Experience of in-silico Immunogenicity assessment is a value addition.
Leadership role (for manager and above level): NA
Preferred Educational background + years of experience: Minimum: M.SC. in Biochemistry / Life Sciences / Biotechnology/M.Tech in Bio-technology.+ 2 to 4 years Preferred: M.SC. in Biochemistry / Life Sciences / Biotechnology + 2 to 5 years Desirable: M.SC. in Biochemistry / Life Sciences / Biotechnology + 2 to 5 years
Additional advantage will be given to person having knowledge or experience of:
Experience in vitro Immunogenicity assessment of peptide products.
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