Job Description

Department DetailsRole SummaryRole Summary

• Relevant experience in mass spectrometry-based characterization of monoclonal antibodies, insulin analogues, pegylated proteins, antibody-drug conjugates, therapeutic peptides, host cell proteins, polysorbates etc
• Experience in handling high-resolution mass spectrometers (Q-TOF/Orbitrap) and familiarity with different software platforms for intact/subunit mass deconvolution, reduced and non-reduced peptide mapping, glycan analysis and other such biopharma applications
• Experience with multi-attribute methods (characterisation and monitoring), new peak detection, generation of automated reports using new generation 'MS only' instruments
• Demonstrated experience in analytical separations with strong chromatography background and willing to cross-learn new skills
• Experience in mass-spec based host-cell protein identification and quantitation, higher-order structure determination using HDX-MS technology, top-down, middle-down and bottom-up approaches of mass spectrometry are desirable
• Experience in biopharmaceutical MS software such as Proteome discoverer, Byonic, Biopharma finder, Protein pilot, Peakview etc, documentation software such eLN, LIMS, QMS software such Trackwise

Key ResponsibilitiesRole Summary

• Relevant experience in mass spectrometry-based characterization of monoclonal antibodies, insulin analogues, pegylated proteins, antibody-drug conjugates, therapeutic peptides, host cell proteins, polysorbates etc
• Experience in handling high-resolution mass spectrometers (Q-TOF/Orbitrap) and familiarity with different software platforms for intact/subunit mass deconvolution, reduced and non-reduced peptide mapping, glycan analysis and other such biopharma applications
• Experience with multi-attribute methods (characterisation and monitoring), new peak detection, generation of automated reports using new generation 'MS only' instruments
• Demonstrated experience in analytical separations with strong chromatography background and willing to cross-learn new skills
• Experience in mass-spec based host-cell protein identification and quantitation, higher-order structure determination using HDX-MS technology, top-down, middle-down and bottom-up approaches of mass spectrometry are desirable
• Experience in biopharmaceutical MS software such as Proteome discoverer, Byonic, Biopharma finder, Protein pilot, Peakview etc, documentation software such eLN, LIMS, QMS software such Trackwise

Educational QualificationsRequired Education Qualification: Msc
Required Experience: 2 - 12 years

Biocon