Job Description

Job Title: Associate Principal AI ScientistCareer Level - DIntroduction to Role:We are seeking a dedicated and innovative Associate Director to join our Biopharmaceuticals R&D team. This role involves developing and applying pharmacokinetic-dynamic models to translate safety findings from nonclinical species to humans. You will work closely with Safety Scientists or Clinical Pharmacologists, and the scope of your work may extend to efficacy data analysis. You will also apply available platform disease models (Quantitative Systems Pharmacology/Toxicology Models) to translate in vitro and in vivo data for clinical study decisions.Accountabilities:As an Associate Director, you will develop and apply mathematical models to translate safety findings from nonclinical species to humans. You will create, expand, or refine mathematical models to address drug discovery and development questions. Your responsibilities will include reviewing, formatting, and analyzing available data for modeling purposes, engaging with project teams, presenting modeling work, staying up-to-date with emerging literature and techniques in modeling and simulation sciences, supporting Safety Scientists and Clinical Pharmacologists with Health Authority queries, and preparing submission documentation related to PKPD analyses for Health Authorities.Essential Skills/Experience:Education Required: Ph.D. in biomedical engineering, applied mathematics, pharmacometrics, or a related field.Overall 10 years of experiecne and More than 2 years experience in data formatting, data analysis post-degree and report writing.Knowledge in physiology, pathology, and/or pharmacology.Capability of parameter estimation and simulation with various what-if scenarios.Effective time management and organizational skills.Self-directed, independent and highly-motivated researcher who excels in a collaborative, multi-disciplinary environment.Excellent oral and written communication skills and the ability to interact effectively with scientists in other subject areas with a positive and collaborative attitude.N/AWhen we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn\'t mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.At AstraZeneca, we are dedicated to doing the science right. We trust in the science. Driven by it and united by it, this is the place where great science comes alive. It's our smart thinking and patience that helps us to push the boundaries of science to deliver life-changing medicines. If you have a true love of science and believe in its potential to redefine the possible, then this is the place for you. We are a team of leading specialists, driven to pursue scientific knowledge. And there's no better place to learn. from the science, from each other and from our failures.Are you ready to make a greater impact? Join us at AstraZeneca where your innovative discoveries will ultimately have the potential to reach billions of patients\' in need, all across the globe. Apply now!Date Posted 26-Aug-2024Closing Date 25-Aug-2024AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca